SYNVISC-ONE® HYLAN G-F 20, 6ml

$339.00

Synvisc-One is a one-time hyaluronic acid injection for knee osteoarthritis that improves joint lubrication and cushioning, offering long-lasting pain relief and enhanced mobility.

Brand: SYNVISC-ONE®
Manufacturer: Genzyme Corporation
Active Substances: Hylan G-F 20 (a cross-linked hyaluronan)
Strength: 6 mL per syringe
Pack Size: 1 pre-filled syringe (6 mL)

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Additional information

SYNVISC-ONE is a state-of-the-art viscosupplement containing Hylan G-F 20, a high-molecular-weight hyaluronan-based substance. Specifically formulated for intra-articular injection, SYNVISC-ONE® mimics the natural synovial fluid present in healthy joints, acting as a cushion and lubricant. Its single-dose convenience makes it a patient-friendly option for managing osteoarthritis pain in the knee, particularly for those who have not responded adequately to non-pharmacological treatments or simple pain relievers.

Indication and Applications

Synvisc-One is indicated for the treatment of pain associated with osteoarthritis of the knee in patients who have not responded adequately to conservative non-pharmacologic therapy and simple analgesics. It helps restore joint function and mobility by improving the lubrication and shock absorption properties of the synovial fluid.

Main Treatment Areas

SYNVISC-ONE is primarily used in the management of knee osteoarthritis. It targets the following treatment objectives:

    • Reducing knee pain associated with mild to moderate osteoarthritis.
    • Enhancing joint mobility and flexibility by replenishing lost or degraded synovial fluid.
    • Delaying or avoiding the need for surgical interventions like knee replacement by offering a non-invasive alternative.
    • Serving as an adjunct to physical therapy or lifestyle modifications for optimal patient outcomes.

Key Benefits

  • Single Injection Convenience: Unlike multi-dose alternatives, SYNVISC-ONE® simplifies treatment with a single 6 mL injection.
  • Proven Pain Relief: Clinical studies demonstrate significant reduction in knee osteoarthritis pain for up to 6 months post-injection.
  • Enhanced Mobility: Helps patients regain their ability to perform daily activities and reduces stiffness.
  • Bioengineered Safety: Manufactured using advanced purification techniques, ensuring a biocompatible solution with minimal adverse effects.
  • Non-Surgical Alternative: Offers an effective, less invasive option compared to surgery for managing chronic knee pain.

 

Safety Information

  • Indications: SYNVISC-ONE® is intended for intra-articular injection in the knee by a qualified healthcare professional.
  • Precautions: Not recommended for patients with known hypersensitivity to hyaluronan products or severe infections at the injection site.
  • Possible Side Effects: Mild joint swelling, localized pain, and redness may occur post-injection but typically subside within days.
  • Contraindications: Avoid in patients with infections or skin diseases near the injection site.
  • Storage: Store between 2°C and 30°C and avoid freezing.

Buy Synvisc-One Hylan G-F 20 – Purchase Information

The SYNVISC-ONE HYLAN G-F 20 is available at a competitive price of $339.00, making it an excellent choice for healthcare providers seeking cost-effective treatment options for patients with knee osteoarthritis. As a single-dose injection, it offers convenience and long-lasting relief, providing value for both patients and clinics. Available through trusted wholesale suppliers, SYNVISC-ONE is an ideal option for bulk orders or individual purchases at wholesale prices, ensuring affordability for healthcare providers managing multiple patients. Dr. Sales Direct is a reliable distributor for securing this product, offering consistent availability and competitive pricing tailored to meet your professional needs.

Frequently Asked Questions

Both Synvisc and Synvisc-One are effective in treating knee osteoarthritis, offering similar efficacy and safety profiles. The main difference is in the dosing regimen: Synvisc requires three weekly injections, while Synvisc-One is a single-dose injection, providing greater convenience. The choice between them often depends on patient preference for fewer doctor visits and the convenience of a single injection​.

Yes, Synvisc-One has been shown to provide significant pain relief for knee osteoarthritis. Many patients experience relief starting from the first month after the injection, with effects lasting up to six months. Individual results can vary, and some patients might respond better than others.

Synvisc-One is not the same as pure hyaluronic acid, but it is derived from hyaluronic acid. Synvisc-One contains hylan G-F 20, a chemically modified form of hyaluronic acid, which helps provide lubrication and cushioning in the knee joint​.

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